B4GALT4

Across TCGA pan-cancer cohorts, B4GALT4 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated B4GALT4 data layer compared with 6 for mutation status and 6 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher B4GALT4 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated B4GALT4 expression acts as an unfavorable survival marker, although some lineages such as UCEC and SKCM show a favorable association.

UCEC, KICH, and LIHC are the cancer types where B4GALT4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Quartile	III,IV	0.743	0.412	.002	74	view →
KICH	DFS	Median	II,III,IV	0.543	0.958	<.001	73	view →
LIHC	OS	Median	All	0.705	0.843	<.001	61	view →
LGG	DFS	Median	All	0.654	0.817	<.001	54	view →
ACC	DFS	Median	All	0.281	0.627	<.001	41	view →
LUAD	DFS	Median	All	0.240	0.451	<.001	38	view →
SKCM	OS	Tertile	All	0.414	0.234	.003	26	view →
PAAD	DFS	Median	All	0.218	0.353	.019	17	view →
MESO	OS	Median	III,IV	0.310	0.705	.022	15	view →
READ	DFS	Median	IV	0.356	0.845	.001	13	view →
HNSC	OS	Quartile	All	0.503	0.755	.017	7	view →
UVM	DFS	Tertile	III,IV	0.317	0.744	.042	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

B4GALT4–UCEC (DFS)

Open the UCEC breakdown →