B4GALT4

Across TCGA pan-cancer cohorts, B4GALT4 RNA differs between tumor and matched normal tissue in 16 of 18 cancer types tested, making tumor–normal expression one of B4GALT4’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where B4GALT4 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types B4GALT4 is over-expressed in tumor, although a few such as KICH and COAD show the opposite, repressed pattern.

BLCA, LUAD, and LIHC are the cancer types where B4GALT4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in B4GALT4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	All	III,IV	+1.433	<.001	9	view →
LUAD	Male	III,IV	+1.161	<.001	9	view →
LIHC	All	II,III,IV	+0.744	<.001	9	view →
LUSC	Female	All	+1.772	<.001	8	view →
HNSC	Male	III,IV	+1.719	<.001	8	view →
BRCA	All	III,IV	+0.646	<.001	8	view →
KICH	Female	II,III,IV	−1.162	<.001	7	view →
CHOL	Male	All	+2.006	<.001	5	view →
STAD	Male	II,III,IV	+0.615	.008	5	view →
COAD	Female	All	−0.512	<.001	5	view →
THCA	Male	III,IV	−0.468	.004	3	view →
READ	All	II,III,IV	−0.352	.005	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 16 lineages.

B4GALT4–BLCA

Open the BLCA breakdown →