B4GALT4

Across TCGA pan-cancer cohorts, B4GALT4 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated B4GALT4 data layer compared with 24 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher B4GALT4 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated B4GALT4 expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCEC show a favorable association.

LUAD, GBM, and HNSC are the cancer types where B4GALT4 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	III,IV	0.640	1.000	.016	11	view →
GBM	OS	Median	All	0.766	0.950	.005	11	view →
HNSC	OS	Median	IV	0.845	0.620	.018	9	view →
CCRCC	OS	Median	All	0.618	1.000	.001	9	view →
UCEC	DFS	Quartile	All	1.000	0.865	.019	4	view →
PDAC	DFS	Median	IV	0.250	0.934	.024	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

B4GALT4–LUAD (OS)

Open the LUAD breakdown →