B4GALT4

Across TCGA pan-cancer cohorts, B4GALT4 mass-spec protein differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of B4GALT4’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where B4GALT4 mass-spec protein is more highly expressed in tumor relative to normal tissue. In most cancer types B4GALT4 is over-expressed in tumor, although a few such as COAD show the opposite, repressed pattern.

LUAD, LSCC, and PDAC are the cancer types where B4GALT4 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in B4GALT4 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	All	III,IV	+0.659	<.001	9	view →
LSCC	Female	II,III,IV	+1.231	<.001	8	view →
PDAC	Male	II,III,IV	+0.590	<.001	8	view →
COAD	All	All	−0.126	.006	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

B4GALT4–LUAD

Open the LUAD breakdown →