B4GALT3

Across TCGA patient cohorts, B4GALT3 mutation is significantly associated with the total protein of many other genes, with 28 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible B4GALT3-associated genes across cancer lineages are p27_pT198, ASNS, and Caspase-7-cleavedD198. Each is linked with B4GALT3 in more than 1 cancer types. Because this analysis shows association rather than direction, both B4GALT3-to-partner and partner-to-B4GALT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, p27_pT198 grouped by B4GALT3-low versus B4GALT3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B4GALT3→partner) and Y-score (partner→B4GALT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p27_pT198 →	+0.096	+1.678	.019	.023	3	2
UCEC	ASNS →	+0.565	+2.906	<.001	.001	3	2
UCEC	Caspase-7-cleavedD198 →	+0.484	+2.135	.033	.010	3	2
UCEC	14-3-3_beta →	-0.100	-2.558	.009	.010	3	1
UCEC	EGFR_pY1068 →	-0.240	-3.459	.012	.005	3	1
UCEC	eIF4G →	+0.247	+1.678	.038	.023	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

p27_pT198 by B4GALT3 expression — UCEC

Explore this box plot interactively →