B4GALNT2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, B4GALNT2 mutation is significantly associated with the RNA expression of many other genes, with 2,273 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible B4GALNT2-associated genes across cancer lineages are MIR4795, RNU1-17P, and FKBP4P2. Each is linked with B4GALNT2 in more than 2 cancer types. Because this analysis shows association rather than direction, both B4GALNT2-to-partner and partner-to-B4GALNT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4795 grouped by B4GALNT2-low versus B4GALNT2-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B4GALNT2→partner) and Y-score (partner→B4GALNT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADMIR4795 →+0.745+3.454<.001.00333
CESCRNU1-17P →+0.378+5.103<.001.00833
BRCAFKBP4P2 →+0.029+3.782.002.00732
UCECMYO19 →+0.506+2.872<.001.00132
SKCMDHRS11 →+0.442+2.622.003<.00132
HNSCRNU6-502P →+0.181+4.327.001.00932
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,273 associations by consensus.

MIR4795 by B4GALNT2 expression — LUAD

Box plot of MIR4795 in B4GALNT2-low vs B4GALNT2-high samples in LUAD.

Explore this box plot interactively →

Exploration