B4GALNT2

Across TCGA pan-cancer cohorts, B4GALNT2 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated B4GALNT2 data layer compared with 5 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher B4GALNT2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated B4GALNT2 expression acts as an unfavorable survival marker, although some lineages such as KIRP and CHOL show a favorable association.

UCEC, SKCM, and LUAD are the cancer types where B4GALNT2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	0.784	0.882	<.001	108	view →
SKCM	OS	Tertile	All	0.785	0.902	<.001	78	view →
LUAD	DFS	Tertile	III,IV	0.228	0.662	<.001	59	view →
STAD	OS	Median	II,III,IV	0.426	0.663	.007	31	view →
DLBC	OS	Tertile	II,III,IV	0.279	1.000	.003	30	view →
LGG	DFS	Tertile	All	0.185	0.487	.004	24	view →
LIHC	OS	Quartile	III,IV	0.372	0.806	.001	23	view →
LUSC	DFS	Tertile	II,III,IV	0.497	0.850	.010	21	view →
KIRP	DFS	Tertile	All	1.000	0.685	.009	21	view →
BRCA	OS	Tertile	All	0.894	0.943	.010	19	view →
HNSC	DFS	Quartile	All	0.594	0.782	.011	14	view →
CHOL	OS	Tertile	All	0.861	0.129	.002	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

B4GALNT2–UCEC (DFS)

Open the UCEC breakdown →