B4GALNT2

Across TCGA cell cohorts, B4GALNT2 mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible B4GALNT2-associated genes across cancer lineages are FAM25G, CRX, and TAAR6. Each is linked with B4GALNT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both B4GALNT2-to-partner and partner-to-B4GALNT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM25G grouped by B4GALNT2-low versus B4GALNT2-high in BONE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B4GALNT2→partner) and Y-score (partner→B4GALNT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	FAM25G →	+1.333	+5.169	<.001	.004	3	2
BLOOD_Myeloma	CRX →	+0.006	+4.807	<.001	.006	3	2
BONE	TAAR6 →	+0.036	+5.169	<.001	.004	3	1
BLOOD_Myeloma	MYF5 →	+0.016	+4.807	<.001	.006	3	1
BLOOD_Myeloma	CFHR5 →	+0.006	+4.807	<.001	.006	3	1
BLOOD_Myeloma	CARTPT →	+0.026	+4.807	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

FAM25G by B4GALNT2 expression — BONE

Explore this box plot interactively →