B4GALNT1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, B4GALNT1 mutation is significantly associated with the RNA expression of many other genes, with 2,087 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible B4GALNT1-associated genes across cancer lineages are CENPU, GHITM, and RRM2. Each is linked with B4GALNT1 in more than 2 cancer types. Because this analysis shows association rather than direction, both B4GALNT1-to-partner and partner-to-B4GALNT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CENPU grouped by B4GALNT1-low versus B4GALNT1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B4GALNT1→partner) and Y-score (partner→B4GALNT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCENPU →+0.552+1.868.002<.00133
UCECGHITM →+0.550+1.980<.001.00233
UCECRRM2 →+0.687+2.021.001.00533
UCECFAM210A →+0.356+1.584.003.00533
UCECPGAM5 →+0.536+1.584<.001.00533
UCECMIR6803 →+0.084+3.571<.001.00933
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,087 associations by consensus.

CENPU by B4GALNT1 expression — UCEC

Box plot of CENPU in B4GALNT1-low vs B4GALNT1-high samples in UCEC.

Explore this box plot interactively →

Exploration