B4GALNT1

Across TCGA patient cohorts, B4GALNT1 mutation is significantly associated with the total protein of many other genes, with 55 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible B4GALNT1-associated genes across cancer lineages are Rictor_pT1135, 14-3-3_beta, and EGFR_pY1068. Each is linked with B4GALNT1 in more than 2 cancer types. Because this analysis shows association rather than direction, both B4GALNT1-to-partner and partner-to-B4GALNT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Rictor_pT1135 grouped by B4GALNT1-low versus B4GALNT1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B4GALNT1→partner) and Y-score (partner→B4GALNT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Rictor_pT1135 →	-0.075	-1.874	.033	.049	3	3
UCEC	14-3-3_beta →	-0.079	-1.847	.023	.049	3	2
UCEC	EGFR_pY1068 →	-0.268	-1.736	.002	.007	3	2
UCEC	A-Raf_pS299 →	-0.157	-2.700	<.001	.005	3	2
UCEC	JNK_pT183_Y185 →	-0.139	-1.427	.017	.024	3	2
UCEC	MEK1 →	+0.410	+2.662	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 55 associations by consensus.

Rictor_pT1135 by B4GALNT1 expression — UCEC

Explore this box plot interactively →