B4GALNT1

Across TCGA cell cohorts, B4GALNT1 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible B4GALNT1-associated genes across cancer lineages are COX6A2, DEFA4, and BPIFB6. Each is linked with B4GALNT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both B4GALNT1-to-partner and partner-to-B4GALNT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COX6A2 grouped by B4GALNT1-low versus B4GALNT1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B4GALNT1→partner) and Y-score (partner→B4GALNT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	COX6A2 →	+0.058	+3.700	<.001	.009	3	1
LARGE_INTESTINE	DEFA4 →	+0.022	+3.700	<.001	.009	3	1
LARGE_INTESTINE	BPIFB6 →	+0.014	+3.700	<.001	.009	3	1
LARGE_INTESTINE	TBC1D21 →	+0.008	+3.700	<.001	.009	3	1
LARGE_INTESTINE	NEUROG1 →	+0.010	+3.514	.004	.001	3	1
LARGE_INTESTINE	CCER1 →	+0.009	+3.562	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

COX6A2 by B4GALNT1 expression — LARGE_INTESTINE

Explore this box plot interactively →