B3GNTL1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, B3GNTL1 mutation is significantly associated with the RNA expression of many other genes, with 1,753 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible B3GNTL1-associated genes across cancer lineages are RN7SL415P, MIR6075, and MIR4465. Each is linked with B3GNTL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both B3GNTL1-to-partner and partner-to-B3GNTL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL415P grouped by B3GNTL1-low versus B3GNTL1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B3GNTL1→partner) and Y-score (partner→B3GNTL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCRN7SL415P →+0.143+5.812<.001.00332
COADMIR6075 →+1.076+4.133<.001.00132
BLCAMIR4465 →+0.311+7.640<.001.00932
UCECRNU6-42P →+0.614+2.152.001.00632
UCECRNU7-90P →+0.289+2.964<.001.00232
UCECRNU6-693P →+0.156+3.400<.001.00332
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,753 associations by consensus.

RN7SL415P by B3GNTL1 expression — CESC

Box plot of RN7SL415P in B3GNTL1-low vs B3GNTL1-high samples in CESC.

Explore this box plot interactively →

Exploration