B3GNT9

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, B3GNT9 mutation is significantly associated with the total protein of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible B3GNT9-associated genes across cancer lineages are Caspase-7-cleavedD198, MEK1, and p62 Lck ligand. Each is linked with B3GNT9 in more than 1 cancer types. Because this analysis shows association rather than direction, both B3GNT9-to-partner and partner-to-B3GNT9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by B3GNT9-low versus B3GNT9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B3GNT9→partner) and Y-score (partner→B3GNT9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCaspase-7-cleavedD198 →+0.699+2.189.014.03432
UCECMEK1 →+0.360+3.000.041.03631
UCECp62 Lck ligand →+0.402+2.459.010.02031
UCECRad50 →-0.301-2.459.010.02031
UCECAnnexin-1 →+0.677+2.189.007.03431
UCECCyclin-B1 →+0.632+3.584.019.00231
Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Caspase-7-cleavedD198 by B3GNT9 expression — UCEC

Box plot of Caspase-7-cleavedD198 in B3GNT9-low vs B3GNT9-high samples in UCEC.

Explore this box plot interactively →

Exploration