B3GNT9

Across TCGA pan-cancer cohorts, B3GNT9 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated B3GNT9 data layer compared with 4 for mutation status and 5 for mass-spec protein.

The strongest signal is observed in brain lower grade glioma (LGG), where higher B3GNT9 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated B3GNT9 expression acts as an unfavorable survival marker, although some lineages such as KIRC and KIRP show a favorable association.

LGG, KIRC, and BLCA are the cancer types where B3GNT9 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LGG	OS	Median	All	0.357	0.523	<.001	50	view →
KIRC	DFS	Tertile	All	0.763	0.482	<.001	47	view →
BLCA	DFS	Tertile	All	0.163	0.543	.002	43	view →
LIHC	OS	Quartile	II,III,IV	0.378	0.733	<.001	33	view →
STAD	OS	Median	All	0.347	0.543	.006	29	view →
ACC	OS	Quartile	All	0.376	1.000	.003	25	view →
MESO	OS	Quartile	III,IV	0.454	0.747	.005	15	view →
KIRP	DFS	Tertile	All	1.000	0.780	.004	14	view →
ESCA	DFS	Tertile	II,III,IV	1.000	0.127	.023	12	view →
THYM	DFS	Median	II,III,IV	0.852	0.604	.018	8	view →
UCS	DFS	Median	IV	0.835	0.490	.031	6	view →
PCPG	DFS	Quartile	All	1.000	0.759	.011	5	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

B3GNT9–LGG (OS)

Open the LGG breakdown →