B3GNT8

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, B3GNT8 mutation is significantly associated with the RNA expression of many other genes, with 81 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible B3GNT8-associated genes across cancer lineages are RCC2P2, SNORA10B, and RNU6-1096P. Each is linked with B3GNT8 in more than 1 cancer types. Because this analysis shows association rather than direction, both B3GNT8-to-partner and partner-to-B3GNT8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RCC2P2 grouped by B3GNT8-low versus B3GNT8-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B3GNT8→partner) and Y-score (partner→B3GNT8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADRCC2P2 →+0.034+7.930<.001.00832
COADSNORA10B →+0.775+4.693<.001.00732
COADRNU6-1096P →+0.448+5.392<.001.00232
BLCAOR5D2P →+0.199+7.640<.001.00932
KIRCRNA5SP34 →+0.292+5.810<.001.00332
KIRCMIR6888 →+0.454+5.377<.001.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 81 associations by consensus.

RCC2P2 by B3GNT8 expression — LUAD

Box plot of RCC2P2 in B3GNT8-low vs B3GNT8-high samples in LUAD.

Explore this box plot interactively →

Exploration