B3GNT7

Across TCGA pan-cancer cohorts, B3GNT7 mass-spec protein differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of B3GNT7’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where B3GNT7 mass-spec protein is repressed in tumor relative to normal tissue. In most cancer types B3GNT7 is over-expressed in tumor, although a few such as COAD and PDAC show the opposite, repressed pattern.

COAD, PDAC, and LUAD are the cancer types where B3GNT7 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in B3GNT7 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	−0.742	<.001	9	view →
PDAC	All	All	−0.593	<.001	6	view →
LUAD	All	All	+0.285	.001	3	view →
HNSC	All	All	−0.333	.043	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

B3GNT7–COAD

Open the COAD breakdown →