B3GNT3

Across TCGA pan-cancer cohorts, B3GNT3 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated B3GNT3 data layer compared with 24 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher B3GNT3 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated B3GNT3 expression acts as an unfavorable survival marker.

LUAD, PDAC, and HNSC are the cancer types where B3GNT3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Tertile	All	0.196	0.820	.001	18	view →
PDAC	OS	Median	III,IV	0.390	0.876	.003	16	view →
HNSC	DFS	Median	III,IV	0.402	0.658	.021	4	view →
LSCC	OS	Tertile	All	0.598	0.900	.033	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

B3GNT3–LUAD (DFS)

Open the LUAD breakdown →