B3GNT2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, B3GNT2 mutation is significantly associated with the RNA expression of many other genes, with 3,760 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible B3GNT2-associated genes across cancer lineages are RNU6-163P, MIR4695, and MIR6846. Each is linked with B3GNT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both B3GNT2-to-partner and partner-to-B3GNT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-163P grouped by B3GNT2-low versus B3GNT2-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B3GNT2→partner) and Y-score (partner→B3GNT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCARNU6-163P →+0.591+4.568<.001.00432
LUSCMIR4695 →+0.638+6.438<.001.00132
LUSCMIR6846 →+0.742+6.578<.001.00132
SKCMRNU6-328P →+0.202+4.199<.001.00932
BLCAPEX5L-AS2 →+0.190+5.623<.001<.00132
SKCMFOXG1-AS1 →+0.178+3.380<.001.00732
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,760 associations by consensus.

RNU6-163P by B3GNT2 expression — BLCA

Box plot of RNU6-163P in B3GNT2-low vs B3GNT2-high samples in BLCA.

Explore this box plot interactively →

Exploration