B3GAT1-DT

Across TCGA pan-cancer cohorts, B3GAT1-DT RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of B3GAT1-DT’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where B3GAT1-DT RNA is repressed in tumor relative to normal tissue. In most cancer types B3GAT1-DT is over-expressed in tumor, although a few such as KIRP and BRCA show the opposite, repressed pattern.

KIRP, THCA, and BRCA are the cancer types where B3GAT1-DT tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in B3GAT1-DT RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	Female	II,III,IV	−1.626	<.001	11	view →
THCA	All	All	+0.292	<.001	9	view →
BRCA	All	III,IV	−0.706	<.001	6	view →
KIRC	Male	All	−0.640	<.001	6	view →
LUSC	Male	II,III,IV	−0.363	<.001	6	view →
KICH	All	All	+1.322	<.001	5	view →
LIHC	Male	All	+0.405	<.001	5	view →
CHOL	All	II,III,IV	+1.894	.032	2	view →
PRAD	All	All	+1.589	<.001	2	view →
READ	Male	All	−1.063	.040	2	view →
READ	Female	All	+1.146	.022	1	view →
COAD	Female	III,IV	−0.981	.034	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

B3GAT1-DT–KIRP

Open the KIRP breakdown →