B3GALT6

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, B3GALT6 mutation is significantly associated with the RNA expression of many other genes, with 747 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible B3GALT6-associated genes across cancer lineages are MIR378G, RNU6-1180P, and BPY2DP. Each is linked with B3GALT6 in more than 1 cancer types. Because this analysis shows association rather than direction, both B3GALT6-to-partner and partner-to-B3GALT6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR378G grouped by B3GALT6-low versus B3GALT6-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B3GALT6→partner) and Y-score (partner→B3GALT6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMMIR378G →+1.189+4.470<.001.00532
COADRNU6-1180P →+0.146+4.602.006.00332
COADBPY2DP →+0.100+4.602<.001.00332
UCECLETM1 →+0.759+3.627<.001.00132
UCECTOR1AIP2 →+0.433+3.202.006.00932
UCECNUP188 →+0.630+3.362.001.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 747 associations by consensus.

MIR378G by B3GALT6 expression — SKCM

Box plot of MIR378G in B3GALT6-low vs B3GALT6-high samples in SKCM.

Explore this box plot interactively →

Exploration