B3GALT6

Across TCGA patient cohorts, B3GALT6 mutation is significantly associated with the total protein of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible B3GALT6-associated genes across cancer lineages are C-Raf, BRD4, and Di-Ras3. Each is linked with B3GALT6 in more than 1 cancer types. Because this analysis shows association rather than direction, both B3GALT6-to-partner and partner-to-B3GALT6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C-Raf grouped by B3GALT6-low versus B3GALT6-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B3GALT6→partner) and Y-score (partner→B3GALT6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	C-Raf →	+0.182	+3.000	.028	.037	3	2
UCEC	BRD4 →	+0.386	+2.814	.018	.036	3	1
UCEC	Di-Ras3 →	-0.207	-3.000	.016	.037	3	1
UCEC	mTOR_pS2448 →	-0.194	-3.000	.024	.037	2	1
UCEC	Tuberin →	+0.533	+3.009	<.001	.019	2	1
UCEC	ATM →	-0.759	-3.000	.003	.037	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

C-Raf by B3GALT6 expression — UCEC

Explore this box plot interactively →