B3GALT4

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, B3GALT4 protein abundance is significantly associated with the RNA expression of many other genes, with 88 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible B3GALT4-associated genes across cancer lineages are TM9SF4, RPAP1, and NMRK1. Each is linked with B3GALT4 in more than 1 cancer types. Because this analysis shows association rather than direction, both B3GALT4-to-partner and partner-to-B3GALT4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, B3GALT4 versus TM9SF4 in BRCA, with a Pearson correlation of -0.83.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B3GALT4→partner) and Y-score (partner→B3GALT4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCATM9SF4 →-0.653-0.413.008.00921
BRCARPAP1 →-0.929-0.413<.001.00921
BRCANMRK1 →-0.869-0.413.006.00921
BRCAMTMR4 →-1.100-0.500.009.00521
BRCADPF1 →+0.257+0.463<.001<.00121
BRCAAKR1D1 →-0.413-0.416.007<.00121
Each partner links to its Q-omics profile. Showing the 6 strongest of 88 associations by consensus.

B3GALT4 vs TM9SF4 — BRCA

Per-sample scatter of B3GALT4 vs TM9SF4 in BRCA (Pearson r = -0.83).

Explore this scatter interactively →

Exploration