B3GALT4

Across TCGA pan-cancer cohorts, B3GALT4 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated B3GALT4 data layer compared with 5 for mutation status.

The strongest signal is observed in sarcoma (SARC), where higher B3GALT4 RNA is associated with better overall survival. In most high-consensus cancer types, elevated B3GALT4 expression acts as an unfavorable survival marker, although some lineages such as SARC and THCA show a favorable association.

SARC, THCA, and SCLC are the cancer types where B3GALT4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SARC	OS	Median	All	0.854	0.633	<.001	47	view →
THCA	OS	Median	III,IV	0.988	0.730	.002	36	view →
SCLC	DFS	Tertile	All	0.714	0.359	<.001	34	view →
MESO	OS	Tertile	All	0.583	0.328	.004	33	view →
UVM	DFS	Median	II,III,IV	0.395	0.730	.004	29	view →
LGG	DFS	Quartile	All	0.708	0.884	.001	22	view →
HNSC	OS	Quartile	All	0.823	0.676	.005	21	view →
KIRC	DFS	Tertile	II,III,IV	0.579	0.419	.020	19	view →
LIHC	DFS	Quartile	III,IV	0.669	0.140	.001	16	view →
BLCA	DFS	Quartile	III,IV	0.614	0.288	.001	14	view →
COAD	DFS	Quartile	II,III,IV	0.460	0.700	.007	12	view →
CHOL	OS	Median	II,III,IV	0.883	0.402	.025	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

B3GALT4–SARC (OS)

Open the SARC breakdown →