B3GALT4

Across TCGA patient cohorts, B3GALT4 mutation is significantly associated with the RNA expression of many other genes, with 802 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible B3GALT4-associated genes across cancer lineages are OR5A2, OR10A7, and ACTL7A. Each is linked with B3GALT4 in more than 1 cancer types. Because this analysis shows association rather than direction, both B3GALT4-to-partner and partner-to-B3GALT4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR5A2 grouped by B3GALT4-low versus B3GALT4-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B3GALT4→partner) and Y-score (partner→B3GALT4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	OR5A2 →	+0.079	+5.040	<.001	.002	3	1
BLCA	OR10A7 →	+0.022	+4.147	.008	.009	3	1
BLCA	ACTL7A →	+0.043	+3.811	<.001	.002	3	1
BLCA	OR2T3 →	+0.022	+4.444	<.001	.006	3	1
BLCA	RNU6-862P →	+0.254	+3.628	.003	.006	3	1
BLCA	RNU6-454P →	+0.136	+4.444	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 802 associations by consensus.

OR5A2 by B3GALT4 expression — BLCA

Explore this box plot interactively →