B3GALNT1

Across TCGA patient cohorts, B3GALNT1 mutation is significantly associated with the RNA expression of many other genes, with 1,629 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible B3GALNT1-associated genes across cancer lineages are RNU6-990P, RN7SL248P, and MYPOP. Each is linked with B3GALNT1 in more than 2 cancer types. Because this analysis shows association rather than direction, both B3GALNT1-to-partner and partner-to-B3GALNT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-990P grouped by B3GALNT1-low versus B3GALNT1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (B3GALNT1→partner) and Y-score (partner→B3GALNT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-990P →	+0.117	+4.769	<.001	.002	3	3
UCEC	RN7SL248P →	+0.059	+3.137	<.001	.005	3	3
UCEC	MYPOP →	+0.371	+2.108	.004	.003	3	2
BRCA	PSAT1P4 →	+0.866	+5.646	<.001	.004	3	2
COAD	RPS23P4 →	+0.245	+5.145	<.001	.007	3	2
COAD	LINC02727 →	+0.226	+6.392	.002	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,629 associations by consensus.

RNU6-990P by B3GALNT1 expression — SKCM

Explore this box plot interactively →