AZU1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, AZU1 mutation is significantly associated with the RNA expression of many other genes, with 337 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible AZU1-associated genes across cancer lineages are RN7SL785P, LRRFIP2P1, and RNU4-58P. Each is linked with AZU1 in more than 1 cancer types. Because this analysis shows association rather than direction, both AZU1-to-partner and partner-to-AZU1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL785P grouped by AZU1-low versus AZU1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AZU1→partner) and Y-score (partner→AZU1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCARN7SL785P →+0.207+5.376<.001.00132
SKCMLRRFIP2P1 →+0.015+4.769<.001.00232
LUSCRNU4-58P →+0.340+6.733<.001<.00132
LUADHSPE1P24 →+0.184+5.984<.001.00232
SKCMMIR6855 →+0.299+2.329.007.00531
SKCMRAB28P4 →+0.039+4.025<.001.00731
Each partner links to its Q-omics profile. Showing the 6 strongest of 337 associations by consensus.

RN7SL785P by AZU1 expression — BLCA

Box plot of RN7SL785P in AZU1-low vs AZU1-high samples in BLCA.

Explore this box plot interactively →

Exploration