AZI2

Across TCGA patient cohorts, AZI2 protein abundance is significantly associated with the RNA expression of many other genes, with 13,528 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AZI2-associated genes across cancer lineages are TACC2, KIF2C, and ITGAM. Each is linked with AZI2 in more than 3 cancer types. Because this analysis shows association rather than direction, both AZI2-to-partner and partner-to-AZI2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AZI2 versus TACC2 in LUAD, with a Pearson correlation of -0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AZI2→partner) and Y-score (partner→AZI2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	TACC2 →	-0.900	-0.153	<.001	.002	3	4
LUAD	KIF2C →	-0.860	-0.149	.006	.003	3	4
GBM	ITGAM →	+0.752	+0.166	.001	.003	3	4
UCEC	ZSWIM1 →	-0.404	-0.320	.003	<.001	3	4
UCEC	ARRDC3-AS1 →	+0.701	+0.274	<.001	.001	3	4
BRCA	ESR1 →	+2.306	+0.182	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,528 associations by consensus.

AZI2 vs TACC2 — LUAD

Explore this scatter interactively →