AZGP1

Across TCGA cell cohorts, AZGP1 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible AZGP1-associated genes across cancer lineages are GKN1, OLIG3, and ELOA3DP. Each is linked with AZGP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both AZGP1-to-partner and partner-to-AZGP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GKN1 grouped by AZGP1-low versus AZGP1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AZGP1→partner) and Y-score (partner→AZGP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GKN1 →	+0.058	+4.095	<.001	.009	3	1
LARGE_INTESTINE	OLIG3 →	+0.024	+4.095	.008	.009	3	1
LARGE_INTESTINE	ELOA3DP →	+0.023	+4.273	.003	.006	3	1
LARGE_INTESTINE	TBC1D3 →	+0.077	+4.273	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

GKN1 by AZGP1 expression — LARGE_INTESTINE

Explore this box plot interactively →