AWAT2

Across TCGA patient cohorts, AWAT2 mutation is significantly associated with the RNA expression of many other genes, with 2,002 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AWAT2-associated genes across cancer lineages are RNA5SP411, RNU7-197P, and RN7SKP286. Each is linked with AWAT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both AWAT2-to-partner and partner-to-AWAT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP411 grouped by AWAT2-low versus AWAT2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AWAT2→partner) and Y-score (partner→AWAT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP411 →	+1.253	+1.730	<.001	.001	3	2
LUAD	RNU7-197P →	+0.558	+7.930	<.001	.008	3	2
SKCM	RN7SKP286 →	+0.068	+5.488	<.001	.001	3	2
SKCM	BMS1P12 →	+0.085	+3.993	<.001	<.001	3	2
UCEC	TRAJ11 →	+0.428	+1.950	<.001	<.001	3	2
UCEC	TRDV3 →	+0.308	+1.702	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,002 associations by consensus.

RNA5SP411 by AWAT2 expression — UCEC

Explore this box plot interactively →