aurora kinase A pseudogene 1Genealiases: AURKAPS1 · AurAps1 · STK6P
Q-omics provides the consensus-scored AURKAP1 profile across patient tissues and cancer cell-line models. AURKAP1 expression is associated with patient survival in 21 of 34 cancer types, with the highest sampling consensus in UCS. Among the 18 cancer types available for tumor–normal comparison, AURKAP1 is differentially expressed in 13, with the highest sampling consensus in BLCA. Additionally, AURKAP1 RNA expression shows 15,825 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight UCS, BLCA, and UVM as cancer lineages where AURKAP1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for AURKAP1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes AURKAP1 survival associations across molecular data types. AURKAP1 RNA expression shows survival associations in the most cancer types (21). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible AURKAP1 RNA expression–survival associations across cancer types. High AURKAP1 expression shows unfavorable associations in ACC, UCEC, KIRP, KIRC and LGG, but favorable associations in UCS. The UCS Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify UCS as the clearest survival context for AURKAP1 RNA expression.
This table summarizes AURKAP1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 13. The strongest signals are observed in BLCA for RNA.
This table ranks reproducible tumor–normal expression differences for AURKAP1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. AURKAP1 shows lower tumor expression in THCA and higher tumor expression in BLCA, HNSC, LUSC, UCEC and STAD. The BLCA box plot shows higher AURKAP1 RNA expression in tumor versus normal tissue (log2 FC = +0.357, t-test p < 0.001).
This table shows molecular features associated with AURKAP1 in patient tissues and cancer cell lines. In patient samples, AURKAP1 shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set. In cancer cell lines, AURKAP1 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in LARGE_INTESTINE.
