AUNIP

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, AUNIP mutation is significantly associated with the RNA expression of many other genes, with 56 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AUNIP-associated genes across cancer lineages are RNA5SP424, LINC01895, and MIR6803. Each is linked with AUNIP in more than 1 cancer types. Because this analysis shows association rather than direction, both AUNIP-to-partner and partner-to-AUNIP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP424 grouped by AUNIP-low versus AUNIP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AUNIP→partner) and Y-score (partner→AUNIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNA5SP424 →+0.268+3.242.002.00732
BRCALINC01895 →+0.623+5.259<.001.00731
UCECMIR6803 →+0.307+5.671<.001<.00131
UCECMIR7851 →+0.437+2.859.006.00631
UCECNPY2R →+0.321+3.086.004.00331
UCECOR1J2 →+0.202+2.566.004.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 56 associations by consensus.

RNA5SP424 by AUNIP expression — UCEC

Box plot of RNA5SP424 in AUNIP-low vs AUNIP-high samples in UCEC.

Explore this box plot interactively →

Exploration