Q-omics provides the consensus-scored MIR7851 profile across patient tissues and cancer cell-line models. MIR7851 expression is associated with patient survival in 16 of 34 cancer types, with the highest sampling consensus in HNSC. Among the 18 cancer types available for tumor–normal comparison, MIR7851 is differentially expressed in 7, with the highest sampling consensus in THCA. Additionally, MIR7851 RNA expression shows 13,090 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight HNSC, THCA, and UVM as cancer lineages where MIR7851 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MIR7851 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MIR7851 survival associations across molecular data types. MIR7851 RNA expression shows survival associations in the most cancer types (16). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MIR7851 RNA expression–survival associations across cancer types. High MIR7851 expression shows unfavorable associations in KIRC, UVM and UCEC, but favorable associations in HNSC, BLCA and BRCA. The HNSC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .005). Together, the overview and detailed table identify HNSC as the clearest survival context for MIR7851 RNA expression.
This table summarizes MIR7851 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 7. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for MIR7851. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MIR7851 shows lower tumor expression in THCA and higher tumor expression in STAD, KIRC, HNSC, LIHC and KICH. The THCA box plot shows higher MIR7851 RNA expression in normal versus tumor tissue (log2 FC = −0.362, t-test p = .038).
This table shows molecular features associated with MIR7851 in patient tissues and cancer cell lines. In patient samples, MIR7851 shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set.
