AUH

Across TCGA pan-cancer cohorts, AUH mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated AUH data layer compared with 23 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher AUH mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated AUH expression acts as an unfavorable survival marker, although some lineages such as PDAC and CCRCC show a favorable association.

PDAC, CCRCC, and LSCC are the cancer types where AUH mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Median	II,III,IV	0.860	0.658	.003	22	view →
CCRCC	DFS	Median	III,IV	1.000	0.451	.032	6	view →
LSCC	OS	Median	II,III,IV	0.877	0.791	.040	3	view →
HNSC	DFS	Quartile	III,IV	0.717	0.429	.027	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

AUH–PDAC (DFS)

Open the PDAC breakdown →