AUH

Across TCGA pan-cancer cohorts, AUH RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of AUH’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where AUH RNA is repressed in tumor relative to normal tissue. In most cancer types AUH is over-expressed in tumor, although a few such as KIRC and KIRP show the opposite, repressed pattern.

KIRC, KIRP, and THCA are the cancer types where AUH tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in AUH RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	II,III,IV	−1.236	<.001	11	view →
KIRP	Male	III,IV	−1.120	<.001	9	view →
THCA	All	All	−0.303	.001	9	view →
COAD	Female	All	−0.669	<.001	7	view →
BRCA	Female	II,III,IV	−0.585	<.001	6	view →
LUAD	Female	II,III,IV	−0.504	.001	5	view →
LUSC	All	All	−0.249	.006	5	view →
UCEC	All	All	−0.539	.001	4	view →
READ	All	All	−0.478	.012	4	view →
LIHC	All	All	+0.294	.003	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

AUH–KIRC

Open the KIRC breakdown →