ATXN3L

Across TCGA patient cohorts, ATXN3L RNA expression is significantly associated with the go_rna of many other GO terms, with 5,482 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible ATXN3L-associated GO terms across cancer lineages are RNA 3'-end processing, Protein localization to chromosome, and Aerobic respiration. Each is linked with ATXN3L in more than 6 cancer types. Because this analysis shows association rather than direction, both ATXN3L-to-partner and partner-to-ATXN3L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA 3'-end processing grouped by ATXN3L-low versus ATXN3L-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATXN3L→partner) and Y-score (partner→ATXN3L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	RNA 3'-end processing →	+0.109	+0.021	<.001	.004	3	7
STAD	Protein localization to chromosome →	+0.113	+0.016	<.001	.001	3	7
STAD	Aerobic respiration →	+0.139	+0.021	<.001	.004	3	7
STAD	Regulation of protein ubiquitination →	+0.108	+0.014	<.001	.005	3	6
STAD	Negative regulation of telomere maintenance via telomere lengthening →	+0.089	+0.028	<.001	.003	2	7
STAD	Positive regulation of RNA binding →	+0.079	+0.015	<.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,482 associations by consensus.

RNA 3'-end processing by ATXN3L expression — STAD

Explore this box plot interactively →