ATXN3L

Across TCGA cell cohorts, ATXN3L RNA expression is significantly associated with the mutation status of many other genes, with 41 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ATXN3L-associated genes across cancer lineages are SBNO1, COL28A1, and CDH24. Each is linked with ATXN3L in more than 1 cancer types. Because this analysis shows association rather than direction, both ATXN3L-to-partner and partner-to-ATXN3L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SBNO1 grouped by ATXN3L-low versus ATXN3L-high in BLOOD_Myeloma.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATXN3L→partner) and Y-score (partner→ATXN3L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	SBNO1 →	+3.906	+0.443	.009	.008	3	1
BLOOD_Myeloma	COL28A1 →	+3.906	+0.443	.009	.008	3	1
LUNG_NSCLC_LUSC	CDH24 →	+4.108	+0.542	.005	.006	3	1
SOFT_TISSUE	PLXNA4 →	+2.936	+0.303	.007	.004	3	1
PANCREAS	NCAPG →	+5.000	+0.035	.006	<.001	3	1
PANCREAS	RDH10 →	+5.000	+0.035	.006	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

SBNO1 by ATXN3L expression — BLOOD_Myeloma

Explore this box plot interactively →