ATXN3

Across TCGA patient cohorts, ATXN3 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,691 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible ATXN3-associated proteins across cancer lineages are PPP4R3A, YLPM1, and CDC42BPB. Each is linked with ATXN3 in more than 6 cancer types. Because this analysis shows association rather than direction, both ATXN3-to-partner and partner-to-ATXN3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATXN3 versus PPP4R3A in COAD, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ATXN3→partner) and Y-score (partner→ATXN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	PPP4R3A →	+0.272	+0.570	<.001	<.001	3	7
GBM	YLPM1 →	+0.260	+0.426	<.001	<.001	3	7
BRCA	CDC42BPB →	+0.305	+0.393	<.001	<.001	3	7
BRCA	NEK9 →	+0.357	+0.445	<.001	<.001	3	6
COAD	PPIF →	-0.446	-0.557	<.001	<.001	3	6
PDAC	ZFYVE1 →	+0.239	+0.282	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,691 associations by consensus.

ATXN3 vs PPP4R3A — COAD

Explore this scatter interactively →