ATXN2L

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ATXN2L protein abundance is significantly associated with the RNA expression of many other genes, with 16,426 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ATXN2L-associated genes across cancer lineages are RAD51AP1, NEK2, and KIF14. Each is linked with ATXN2L in more than 8 cancer types. Because this analysis shows association rather than direction, both ATXN2L-to-partner and partner-to-ATXN2L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATXN2L versus RAD51AP1 in LSCC, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATXN2L→partner) and Y-score (partner→ATXN2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCRAD51AP1 →+1.172+0.228<.001<.00139
BRCANEK2 →+1.277+0.241<.001<.00139
LSCCKIF14 →+1.080+0.268<.001<.00139
LSCCKIF18A →+1.047+0.242<.001<.00139
GBMTOP2A →+1.353+0.199<.001<.00139
GBMKIF23 →+0.933+0.151<.001.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 16,426 associations by consensus.

ATXN2L vs RAD51AP1 — LSCC

Per-sample scatter of ATXN2L vs RAD51AP1 in LSCC (Pearson r = 0.42).

Explore this scatter interactively →

Exploration