Across TCGA patient cohorts, ATXN1L protein abundance is significantly associated with the RNA expression of many other genes, with 6,101 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible ATXN1L-associated genes across cancer lineages are CMTR2, IST1, and NIP7. Each is linked with ATXN1L in more than 4 cancer types. Because this analysis shows association rather than direction, both ATXN1L-to-partner and partner-to-ATXN1L results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATXN1L→partner) and Y-score (partner→ATXN1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CMTR2 →	+0.529	+0.332	.001	.003	3	5
BRCA	IST1 →	+0.365	+0.260	<.001	<.001	3	5
LSCC	NIP7 →	+0.413	+0.155	.003	.005	3	4
OV	TMEM170A →	+0.546	+0.377	<.001	<.001	3	4
OV	TERF2IP →	+0.395	+0.191	.001	.008	3	4
LSCC	TANGO6 →	+0.420	+0.223	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,101 associations by consensus.

Exploration

ATXN1L survival (RNA) · tumor vs normal (RNA) · all ATXN1L data types