Across TCGA cell cohorts, ATXN1L RNA expression is significantly associated with the go_rna of many other GO terms, with 4,753 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ATXN1L-associated GO terms across cancer lineages are Regulation of mRNA splicing, via spliceosome, mRNA transport, and Macroautophagy. Each is linked with ATXN1L in more than 18 cancer types. Because this analysis shows association rather than direction, both ATXN1L-to-partner and partner-to-ATXN1L results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATXN1L→partner) and Y-score (partner→ATXN1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of mRNA splicing, via spliceosome →	+0.112	+0.827	<.001	<.001	3	18
OESOPHAGUS	mRNA transport →	+0.140	+0.821	.006	.001	2	19
STOMACH	Macroautophagy →	+0.081	+0.865	<.001	<.001	3	17
BLOOD_Lymphoma	Nuclear export →	+0.103	+1.178	<.001	<.001	3	17
OESOPHAGUS	Regulation of organelle assembly →	+0.076	+0.882	<.001	<.001	3	17
LARGE_INTESTINE	Negative regulation of DNA-templated transcription initiation →	+0.148	+0.993	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,753 associations by consensus.

Exploration

ATXN1L survival (RNA) · tumor vs normal (RNA) · all ATXN1L data types