Across TCGA cell cohorts, ATXN1L mutation is significantly associated with the RNA expression of many other genes, with 29 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ATXN1L-associated genes across cancer lineages are FBXW10, SLC35G3, and SOX14. Each is linked with ATXN1L in more than 1 cancer types. Because this analysis shows association rather than direction, both ATXN1L-to-partner and partner-to-ATXN1L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATXN1L→partner) and Y-score (partner→ATXN1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	FBXW10 →	+0.201	+3.491	.002	.004	3	2
SOFT_TISSUE	SLC35G3 →	+0.011	+4.635	<.001	.003	3	1
SOFT_TISSUE	SOX14 →	+0.921	+4.882	<.001	.001	3	1
SOFT_TISSUE	CCR8 →	+0.016	+4.369	<.001	.008	3	1
SOFT_TISSUE	GPX6 →	+0.019	+5.954	<.001	<.001	3	1
BLOOD_Myeloma	SERPINA7 →	+0.459	+4.807	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

Exploration

ATXN1L survival (RNA) · tumor vs normal (RNA) · all ATXN1L data types