ATRNL1

Across TCGA cell cohorts, ATRNL1 mutation is significantly associated with the RNA expression of many other genes, with 166 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ATRNL1-associated genes across cancer lineages are RCHY1, RESP18, and MAGEB5. Each is linked with ATRNL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATRNL1-to-partner and partner-to-ATRNL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RCHY1 grouped by ATRNL1-low versus ATRNL1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATRNL1→partner) and Y-score (partner→ATRNL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	RCHY1 →	+0.668	+3.067	.007	.009	3	2
LUNG_NSCLC_LUAD	RESP18 →	+0.013	+2.362	<.001	.008	3	2
LUNG_NSCLC_LUSC	MAGEB5 →	+0.033	+4.643	<.001	.008	3	1
LUNG_NSCLC_LUSC	CXorf51A →	+0.066	+4.643	<.001	.008	3	1
OESOPHAGUS	AHSP →	+0.399	+4.017	.002	.007	3	1
OESOPHAGUS	TBL1Y →	+0.476	+4.392	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 166 associations by consensus.

RCHY1 by ATRNL1 expression — LARGE_INTESTINE

Explore this box plot interactively →