ATRN

Across TCGA cell cohorts, ATRN RNA expression is significantly associated with the go_rna of many other GO terms, with 3,990 significant associations in total. CNS shows the largest number of these associations.

The most reproducible ATRN-associated GO terms across cancer lineages are Endosomal transport, Regulation of peroxisome organization, and Positive regulation of hydrolase activity. Each is linked with ATRN in more than 14 cancer types. Because this analysis shows association rather than direction, both ATRN-to-partner and partner-to-ATRN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosomal transport grouped by ATRN-low versus ATRN-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATRN→partner) and Y-score (partner→ATRN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Endosomal transport →	+0.057	+1.042	<.001	<.001	3	15
STOMACH	Regulation of peroxisome organization →	+0.208	+1.767	<.001	<.001	3	15
OESOPHAGUS	Positive regulation of hydrolase activity →	+0.059	+0.850	<.001	.001	3	14
UPPER_AERODIGESTIVE_TRACT	Regulation of protein localization to endoplasmic reticulum →	+0.140	+1.224	<.001	<.001	3	14
STOMACH	Lysosome organization →	+0.053	+1.101	.004	.002	3	14
STOMACH	Lytic vacuole organization →	+0.053	+1.101	.004	.002	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,990 associations by consensus.

Endosomal transport by ATRN expression — OESOPHAGUS

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