ATRIP

Across TCGA cell cohorts, ATRIP mutation is significantly associated with the mutation status of many other genes, with 2,597 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ATRIP-associated genes across cancer lineages are LPO, LZTS2, and EPHB6. Each is linked with ATRIP in more than 4 cancer types. Because this analysis shows association rather than direction, both ATRIP-to-partner and partner-to-ATRIP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LPO grouped by ATRIP-low versus ATRIP-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATRIP→partner) and Y-score (partner→ATRIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	LPO →	+5.502	+5.502	.003	.003	1	5
SKIN	LZTS2 →	+5.392	+4.824	.004	.004	1	4
BLOOD_Leukemia	EPHB6 →	+2.572	+4.129	.009	.009	1	4
BLOOD_Leukemia	CCDC88B →	+2.779	+4.326	.006	.006	1	4
BLOOD_Leukemia	ACAN →	+2.894	+4.432	.005	.005	1	4
SOFT_TISSUE	PLXNB1 →	+5.502	+5.502	.003	.003	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,597 associations by consensus.

LPO by ATRIP expression — SOFT_TISSUE

Explore this box plot interactively →