ATP9B

Across TCGA patient cohorts, ATP9B mutation is significantly associated with the RNA expression of many other genes, with 3,257 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATP9B-associated genes across cancer lineages are RN7SL248P, TNNC2, and SAP30. Each is linked with ATP9B in more than 2 cancer types. Because this analysis shows association rather than direction, both ATP9B-to-partner and partner-to-ATP9B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by ATP9B-low versus ATP9B-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP9B→partner) and Y-score (partner→ATP9B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RN7SL248P →	+0.111	+5.033	<.001	.003	3	3
COAD	TNNC2 →	-2.238	-3.584	<.001	.002	3	3
UCEC	SAP30 →	+0.442	+1.895	<.001	.001	3	3
UCEC	SFXN1 →	+0.431	+3.021	<.001	<.001	3	3
UCEC	RASSF1-AS1 →	+0.378	+2.291	<.001	<.001	3	3
UCEC	PTP4A3 →	-0.735	-4.574	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,257 associations by consensus.

RN7SL248P by ATP9B expression — BLCA

Explore this box plot interactively →