ATP8B3

Across TCGA patient cohorts, ATP8B3 protein abundance is significantly associated with the RNA expression of many other genes, with 850 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ATP8B3-associated genes across cancer lineages are EEF1A1P12, CDADC1, and ZNF14. Each is linked with ATP8B3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP8B3-to-partner and partner-to-ATP8B3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATP8B3 versus EEF1A1P12 in COAD, with a Pearson correlation of -0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP8B3→partner) and Y-score (partner→ATP8B3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	EEF1A1P12 →	-1.044	-1.275	.001	<.001	3	2
PDAC	CDADC1 →	+0.293	+1.770	.005	.001	3	1
PDAC	ZNF14 →	+0.407	+1.808	.001	.002	3	1
PDAC	AGFG2 →	+0.780	+2.436	.009	<.001	3	1
PDAC	PHYH →	+0.722	+1.917	.002	.005	3	1
PDAC	SLC16A6 →	-0.935	-2.008	.004	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 850 associations by consensus.

ATP8B3 vs EEF1A1P12 — COAD

Explore this scatter interactively →