ATP8B1

Across TCGA patient cohorts, ATP8B1 protein abundance is significantly associated with the RNA expression of many other genes, with 19,355 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ATP8B1-associated genes across cancer lineages are TC2N, MRAS, and PRNP. Each is linked with ATP8B1 in more than 5 cancer types. Because this analysis shows association rather than direction, both ATP8B1-to-partner and partner-to-ATP8B1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATP8B1 versus TC2N in BRCA, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP8B1→partner) and Y-score (partner→ATP8B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TC2N →	+1.064	+0.439	<.001	.001	3	6
BRCA	MRAS →	-0.977	-0.672	<.001	<.001	3	5
BRCA	PRNP →	-0.870	-0.571	<.001	<.001	3	5
BRCA	TUBB6 →	-1.163	-0.558	<.001	<.001	3	5
BRCA	C9orf152 →	+1.709	+0.539	<.001	<.001	3	5
BRCA	BCAS1 →	+2.538	+0.848	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,355 associations by consensus.

ATP8B1 vs TC2N — BRCA

Explore this scatter interactively →