ATP8B1

Across TCGA cell cohorts, ATP8B1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,099 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ATP8B1-associated GO terms across cancer lineages are Vestibulocochlear nerve formation, Regulation of chloride transport, and Aminophospholipid translocation. Each is linked with ATP8B1 in more than 18 cancer types. Because this analysis shows association rather than direction, both ATP8B1-to-partner and partner-to-ATP8B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vestibulocochlear nerve formation grouped by ATP8B1-low versus ATP8B1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP8B1→partner) and Y-score (partner→ATP8B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Vestibulocochlear nerve formation →	+1.867	+3.318	<.001	<.001	3	19
SOFT_TISSUE	Regulation of chloride transport →	+1.436	+2.686	<.001	<.001	3	17
LIVER	Aminophospholipid translocation →	+0.202	+3.022	<.001	<.001	3	13
OESOPHAGUS	Regulation of blood-brain barrier permeability →	+0.258	+1.383	<.001	.001	3	13
STOMACH	Positive regulation of sodium ion transmembrane transport →	+0.179	+1.691	.003	<.001	3	12
LUNG_SCLC	Regulation of potassium ion import →	+0.221	+2.300	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,099 associations by consensus.

Vestibulocochlear nerve formation by ATP8B1 expression — BONE

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