ATP8A2

Across TCGA patient cohorts, ATP8A2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,490 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ATP8A2-associated genes across cancer lineages are METTL21EP, RNU6-1255P, and LINC02344. Each is linked with ATP8A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP8A2-to-partner and partner-to-ATP8A2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATP8A2 versus METTL21EP in GBM, with a Pearson correlation of 0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP8A2→partner) and Y-score (partner→ATP8A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	METTL21EP →	+0.378	+0.541	.001	.009	3	2
BRCA	RNU6-1255P →	+0.809	+1.385	.004	.004	3	1
BRCA	LINC02344 →	+0.178	+1.313	.004	.008	3	1
BRCA	SLC25A53 →	-0.395	-0.467	.002	.002	3	1
GBM	PRODH →	+0.930	+0.699	<.001	<.001	3	1
GBM	SEZ6L →	+1.289	+0.487	.009	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,490 associations by consensus.

ATP8A2 vs METTL21EP — GBM

Explore this scatter interactively →