ATP8A2

Across TCGA patient cohorts, ATP8A2 mutation is significantly associated with the RNA expression of many other genes, with 7,244 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATP8A2-associated genes across cancer lineages are SNRPGP7, JOSD1, and RAN. Each is linked with ATP8A2 in more than 4 cancer types. Because this analysis shows association rather than direction, both ATP8A2-to-partner and partner-to-ATP8A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNRPGP7 grouped by ATP8A2-low versus ATP8A2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP8A2→partner) and Y-score (partner→ATP8A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SNRPGP7 →	+0.280	+2.902	<.001	.002	3	5
UCEC	JOSD1 →	+0.522	+2.459	<.001	<.001	3	4
UCEC	RAN →	+0.476	+1.736	<.001	<.001	3	4
COAD	EIF5A →	+0.392	+2.249	.009	.006	3	4
UCEC	TTC5 →	+0.309	+1.959	<.001	.001	3	4
UCEC	PRPSAP2 →	+0.436	+3.545	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,244 associations by consensus.

SNRPGP7 by ATP8A2 expression — COAD

Explore this box plot interactively →